Endocrine Abstracts

ObjectivePrimary hyperparathyroidism (PHPT) is the most common cause of hypercalcemia. A group of patients who were followed up with a diagnosis of PHPT had normal calcium levels with high parathyroid hormone (PTH) levels. For the diagnosis of normocalcemic PHPT, secondary causes of hyperparathyroidism such as vitamin D deficiency should be excluded. In this study, the data of 318 PHPT patients who were operated were retrospectively analyzed, and biochem...

BackgroundWe aimed to determine the awareness of obese, overweight and normal weight patients about the complications, causes and prevention of obesity.MethodsPatients who admitted to our clinic during a four months period were included. Demographical features, familial histories of obesity, smoking, alcohol use, chronic diseases, medications, medical nutrition therapy and exercise habits were determined. Ans...

Background: Medullary thyroid cancers (MTC) originate from parafollicular C cells and constitute 3-5% of all thyroid cancers. Calcitonin (CT) measurement is useful in the diagnosis of MTC. The sensitivity and specificity of CT are low in the measurement alone, and the sensitivity and specificity increase when used with pentagastrin and calcium stimulation tests. However, the difficulty of accessing pentagastrin, the uncertainty of the cut-off value in calcium stimulation tests...

Backgorund: Adrenal incidentalomas (AI) are lesions discovered incidentally on imaging without clinical symptoms or examination findings. AI can produce hormones in 5-30% of cases. Autonomic cortisol secretion (ACS) is the most common of these. Although ACS is asymptomatic, it increases the risk of metabolic disorders.Methods: Patients aged<18 years with adrenal adenoma and upper abdominal MRI who presented and were examined in the endocrinology outp...

Introduction: Insulinoma is a rare neuroendocrine tumor that is difficult to diagnose due to its obscure location. Conventional radiographic methods have low sensitivity and are inadequate to detect insulinoma. Selective arterial calcium stimulation test (SACST) is 95–100% sensitive in the diagnosis of insulinomas. Here, we presented two cases of insulinoma that could not be located by radiographic methods and evaluated them with SACST.Case 1: A 48-...

Aim: To determine whether early repeat fine needle aspiration biopsy(FNAB) has an effect on adequate or atypia of undetermined significance/follicular lesion of undetermined significance(AUS/FLUS) cytology rates in thyroid nodules with inadequate or AUS/FLUS in the first FNAB.Method: Nodules of patients who underwent repeat biopsy due to insufficient or AUS/FLUS cytology between 2019-2022 were included. Demographic data of the patients and ultrasonograph...

Aim: Contradictory results in limited number of studies were reported about the effects of Ramadan fasting on thyroid hormones. We aimed to evaluate the thyroid functions in Ramadan, and compare late evening or pre-sahour use of levothyroxine in patients being treated for hypothyroidism.Methods: Patients taking levothyroxine for hypothyroidism who were seen in the last one week before Ramadan (8–15 May 2018) and had normal thyroid functions were rec...

Introduction: Upper gastrointestinal (UGI) symptoms are frequently encountered in patients with primary hyperparathyroidism (PHPT). Some of these symptoms may improve after PHPT treatment, while hypercalcemic state may also cause permanent effects. We aimed to evaluate UGI symptoms, UGI endoscopic and pathologic features and determine the relationship between these features with serum chromogranin A (CgA) and gastrin in PHPT patients.Methods: Seventy-one...

Introduction: Although, familial medullary thyroid cancer is a known condition, familial papillary thyroid cancer (PTC) is a rare and less well described clinical entity. While some studies suggest more aggressive features in familial PTC, some do not support these findings. We aimed to compare ultrasonographical, cytopathological and histopathological results of patients with familial and sporadic PTC.Methods: Data of 194 patients diagnosed with PTC his...

Introduction: Recently, it has been suggested that thyrotropin (TSH) concentration can be used as a marker for prediction of thyroid malignancy. However, the association between the cytology results and TSH levels is not clear. In this study, we aimed to investigate the relationship between TSH levels and Bethesda categories and determine the role of TSH levels in prediction of malignancy in patients with different Bethesda categories.Methods: The data o...